Because of the slow flow in the venous spaces of large-vessel hemangiomas,
demonstration of color flow signals with conventional color Doppler or powe
r Doppler sonography may be difficult. We report the case of a 22-year-old
female patient with a soft tissue tumor containing multiple fluid-filled sp
aces in the right supraclavicular region. Gray-scale, color, and power Dopp
ler sonography could not differentiate between cystic lymphangioma and larg
e-vessel hemangioma. The intravenous echo-enhancing contrast agent Levovist
was administered, and a significant echo-enhancing effect on color and pow
er Doppler imaging was demonstrated in the fluid-filled spaces and lasted f
or about 3 minutes. Histopathologic study of the excised tumor confirmed th
e sonographic diagnosis of hemangioma. Levovist appears useful in depicting
slow flow in a large-vessel hemangioma. (C) 1999 John Wiley & Sons, Inc.