The purpose of the current study was to examine the impact of massage thera
py on psychological, physical and psychophysiological measures in patients
undergoing autologous bone marrow transplantation (BMT). Patients scheduled
to undergo BMT were randomly assigned to receive either (a) massage therap
y, consisting of 20-minute sessions of shoulder, neck, head, and facial mas
sage, or (b) standard treatment. Overall effects of massage therapy on anxi
ety, depression, and mood were assessed pretreatment, midtreatment, and pri
or to discharge using the State-Trait Anxiety inventory, Beck Depression In
ventory, and Brief Profile of Mood States, respectively. The immediate effe
cts of massage were measured via the State Anxiety Inventory, Numerical Sca
les of Distress, Fatigue, Nausea, and Pain and indices of psychophysiologic
al arousal (heart rate, blood pressure and respiration, rate), collected pr
ior to and following patients' first, fifth, and final massage (on Days -7,
midtreatment, and predischarge). Analysis of the data evaluating the effec
ts of massage showed that patients in the massage therapy group demonstrate
d significantly larger reductions in distress, fatigue, nausea, and State A
nxiety than the standard treatment group at Day -7, in State Anxiety at mid
treatment, and in fatigue at the predischarge assessment. The overall measu
res of psychological symptoms measured at pretreatment, midtreatment, and p
rior to discharge showed no overall group differences, although the massage
group scored significantly lower on the State Anxiety Inventory than the s
tandard care group at the midtreatment assessment. The two groups together
showed significant declines through time on scores from the profile of Mood
States and State and Trait Anxiety Inventories. (C) U.S. Cancer Pain Relie
f Committee, 1999.