Citation
J. Reiffers et al., Abrogation of post-myeloablative chemotherapy neutropenia by ex-vivo expanded autologous CD34-positive cells, LANCET, 354(9184), 1999, pp. 1092-1093
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736
→ ACNP
Volume
354
Issue
9184
Year of publication
1999
Pages
1092 - 1093
Database
ISI
SICI code
0140-6736(19990925)354:9184<1092:AOPCNB>2.0.ZU;2-L
Abstract
We show that absolute and severe neutropenia after high-dose therapy with m
elphalan with or without total body irradiation can be abrogated by cells g
enerated ex vivo. This may change the clinical practice of haematopoietic c
ell transplantation and high-dose chemotherapy because the morbidity and ho
spitalisation associated with neutropenia could be avoided or reduced.