Total hypotrichosis: genetic form of alopecia not linked to hairless gene

Authors
Rogaev, EI Zinchenko, RA Dvoryachikov, G Sherbatich, T Ginter, EK
Citation
Ei. Rogaev et al., Total hypotrichosis: genetic form of alopecia not linked to hairless gene, LANCET, 354(9184), 1999, pp. 1097-1098
Citations number
5
Categorie Soggetti
General & Internal Medicine","Medical Research General Topics
Journal title
LANCET
ISSN journal
01406736 → ACNP
Volume
354
Issue
9184
Year of publication
1999
Pages
1097 - 1098
Database
ISI
SICI code
0140-6736(19990925)354:9184<1097:THGFOA>2.0.ZU;2-K
Abstract
We describe a hereditary form of alopecia in an aboriginal Finno-Ugric popu lation. Linkage and mutation analyses of 21 families showed that the disord er was not linked to the hairless gene on chromosome 8. This implies that a n isolated hairless defect caused by a single gene is a genetically heterog eneous disorder in human populations.