Chemoenzymatic syntheses of optically active polyacrylates

Different primary alcohols were transesterified using Mucor meihei lipase. 2,3-Butanedione monoxime acrylate was used efficiently as an acrylating age nt to synthesize optically active acrylates. The effects of substrate subst itution and solvent on the reaction rate were studied. The results showed t hat the reaction rates in nonpolar solvents were the fastest for acryloylat ing reactions reported until now. The enantiomeric excess (ee) and enantiom eric purity (E value) of all the acrylate monomers were evaluated and compa red. The synthesized optically active acrylate monomers were polymerized by the free-radical initiation technique.