Pd. Scariati et al., A LONGITUDINAL ANALYSIS OF INFANT MORBIDITY AND THE EXTENT OF BREAST-FEEDING IN THE UNITED-STATES, Pediatrics, 99(6), 1997, pp. 51-55
Background. Studies on the health benefits of breastfeeding in develop
ed countries have shown conflicting results. These studies often fail
to account for confounding, reverse causality, and dose-response effec
ts. We addressed these issues in analyzing longitudinal data to determ
ine if breastfeeding protects US infants from developing diarrhea and
ear infections. Methods. Mothers participating in a mail panel provide
d information on their infants at ages 2, 3, 4, 5, 6, and 7 months. In
fants were classified as exclusively breastfed; high, middle, or low m
ixed breast- and formula-fed; or exclusively formula-fed. Diarrhea and
ear infection diagnoses were based on mothers' reports. Infant age an
d gender; other liquid and solid intake; maternal education, occupatio
n, and smoking; household size; family income; and day care use were a
djusted for in the full models. Results. The risk of developing either
diarrhea or ear infection increased as the amount of breast milk an i
nfant received decreased. In the full models, the risk for diarrhea re
mained significant only in infants who received no breast milk compare
d with those who received only breast milk (odds ratio = 1.8); the ris
k for ear infection remained significant in the low mixed feeding grou
p (odds ratio = 1.6) and among infants receiving no breast milk compar
ed with those who received only breast milk (odds ratio = 1.7). Conclu
sions. Breastfeeding protects US infants against the development of di
arrhea and ear infection. Breastfeeding does not have to be exclusive
to confer this benefit. In fact, protection is afforded in a dose-resp
onse manner. The more breast milk an infant receives in the first 6 mo
nths of life, the less likely that he or she will develop diarrhea or
ear infection.