An improved oxidation of an alcohol using aqueous permanganate and phase-transfer catalyst

Authors
Mahmood, A Robinson, GE Powell, L
Citation
A. Mahmood et al., An improved oxidation of an alcohol using aqueous permanganate and phase-transfer catalyst, ORG PROC R, 3(5), 1999, pp. 363-364
Citations number
4
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
ORGANIC PROCESS RESEARCH & DEVELOPMENT
ISSN journal
10836160 → ACNP
Volume
3
Issue
5
Year of publication
1999
Pages
363 - 364
Database
ISI
SICI code
1083-6160(199909/10)3:5<363:AIOOAA>2.0.ZU;2-K
Abstract
The oxidation of a primary alcohol to the corresponding carboxylic acid via permanganate and phase-transfer catalyst has been modified to circumvent i mpurity formation incurred during the reaction. A safe, simple, and efficie nt process was developed which gave the required carboxylic acid in 77% iso lated yield using sodium permanganate in the presence of tetraethylammonium hydrogen sulphate.