Microbial hydroxylation of natural drimenic lactones

Citation
M. Maurs et al., Microbial hydroxylation of natural drimenic lactones, PHYTOCHEM, 52(2), 1999, pp. 291-296
Citations number
20
Categorie Soggetti
Agricultural Chemistry","Animal & Plant Sciences
Journal title
PHYTOCHEMISTRY
ISSN journal
00319422 → ACNP
Volume
52
Issue
2
Year of publication
1999
Pages
291 - 296
Database
ISI
SICI code
0031-9422(199909)52:2<291:MHONDL>2.0.ZU;2-8
Abstract
Incubation of confertifolin and isodrimenin with Mucor plumbeus, Aspergillu s niger or Rhizopus arrhizus gave in good yields the corresponding 3 beta-h ydroxy derivatives. From isodrimenin, the known natural 7 alpha-hydroxy der ivative (futronolide) was also obtained and its structure was definitely es tablished by X-ray crystallographic study of its acetate derivative. (C) 19 99 Elsevier Science Ltd. All rights reserved.