Preparation of thermosensitive hydrogel (PP-g-NIPAAm) with one-off switching for controlled release of drugs

Authors
Wu, MH Bao, BR Chen, J Xu, YJ Zhao, SR Ma, ZT
Citation
Mh. Wu et al., Preparation of thermosensitive hydrogel (PP-g-NIPAAm) with one-off switching for controlled release of drugs, RADIAT PH C, 56(3), 1999, pp. 341-346
Citations number
10
Categorie Soggetti
Physics
Journal title
RADIATION PHYSICS AND CHEMISTRY
ISSN journal
0969806X → ACNP
Volume
56
Issue
3
Year of publication
1999
Pages
341 - 346
Database
ISI
SICI code
0969-806X(199909)56:3<341:POTH(W>2.0.ZU;2-8
Abstract
A novel thermosensitive hydrogel with high mechanical strength was obtained by grafting N-isopropylacrylamide (NIPAAm) onto polypropylene using a prei rradiation grafting method. The effect of radiation dose, dose rate, grafti ng temperature and reaction time on the grafting degree and properties of s welling-deswelling is discussed. Water absorption of the grafted polypropyl ene film could be switched on and off swiftly by control of temperature. Th e microstructure of grafted ultra thin porous PP film was studied with scan ning electron microscope. (C) 1999 Elsevier Science Ltd. All rights reserve d.