A facile one pot synthesis of highly substituted 1,6-naphthyridines

Authors
Murugan, P Raghukumar, V Ramakrishnan, VT
Citation
P. Murugan et al., A facile one pot synthesis of highly substituted 1,6-naphthyridines, SYN COMMUN, 29(22), 1999, pp. 3881-3887
Citations number
15
Categorie Soggetti
Organic Chemistry/Polymer Science
Journal title
SYNTHETIC COMMUNICATIONS
ISSN journal
00397911 → ACNP
Volume
29
Issue
22
Year of publication
1999
Pages
3881 - 3887
Database
ISI
SICI code
0039-7911(1999)29:22<3881:AFOPSO>2.0.ZU;2-N
Abstract
The synthesis of 1,6-naphthyridines 2a-f by the reaction of chalcones 1a-f with malononitrile in the presence of pyrrolidine, involving the Michael ad dition followed by Thorpe-Ziegler cyclization is described.