S. Seidinger et al., The muscle relaxant rocuroniumbromid (Esmeron (R)) and its effect on the intraocular pressure and globe position in the dog, WIEN TIER M, 86(9), 1999, pp. 301-305
In 11 dogs the effect of rocuroniumbromid on intraocular pressure and globe
position was examined. For standard anaesthesia glykopyrrolat, medetomidin
e, and butorphanol were used for premedication and isoflurane to continue a
naesthesia. The Tone-Pen XLS was used to measure intraocular pressure and t
he TOF-GUARD(R), a nerve stimulating device, to control the neuromuscular b
lockade (onset time, duration of effect, recovery time). Rocuroniumbromid c
aused a decrease in intraocular pressure of no clinical relevance, the bulb
i rotated upwards before the end of onset time and remained in central posi
tion after the end of the neuromuscular blockade as well.