Nerve-sparing surgery for advanced rectal cancer patients: Special reference to Dukes C patients

Several nerve-sparing operations for advanced rectal cancer that aim to pre serve genitourinary function without compromising tumor clearance have been developed in Japan. The aim of this study was to evaluate the survival and local recurrence of these procedures in Dukes B and C patients. A total of 177 patients with advanced rectal cancer underwent curative nerve-sparing surgery (NSS) over the last 11 Sears; 52 were Dukes B patients and 54 were Dukes C. Altogether 36 had Dukes C1 and 18 had Dukes C2 tumors, 13 with lat eral lymph node metastases, designated lateral LN(+). The 5-year survival r ate was 92% for Dukes B, 67% for Dukes C1, and 39% for Dukes C2 patients: 1 1% for Dukes C2 patients with lateral LN(+). The local recurrence rate was 6% for Dukes B, 11% for Dukes C1, and 33% for Dukes C2 patients: 20% for th e lateral LN(-) group and 39% for the lateral LN(+) group. Almost all of th e patients undergoing NSS could micturate spontaneously, but preservation o f sexual function was not as successful. Although there is no guarantee of preserving satisfactory sexual function, our NSS is an acceptable procedure for Dukes B, C1, and C2 patients without lateral lymph node metastases.