Atenolol versus amlodipine versus isosorbide-5-mononitrate on anginal symptoms in syndrome X

Authors
Lanza, GA Colonna, G Pasceri, V Maseri, A
Citation
Ga. Lanza et al., Atenolol versus amlodipine versus isosorbide-5-mononitrate on anginal symptoms in syndrome X, AM J CARD, 84(7), 1999, pp. 854
Citations number
20
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
AMERICAN JOURNAL OF CARDIOLOGY
ISSN journal
00029149 → ACNP
Volume
84
Issue
7
Year of publication
1999
Database
ISI
SICI code
0002-9149(19991001)84:7<854:AVAVIO>2.0.ZU;2-S
Abstract
The effects of a beta blocker (atenolol), a calcium antagonist (amlodipine) , and a nitrate (isosorbide-5-mononitrate) on anginal symptoms in 10 patien ts with syndrome X were assessed in a crossover, double-blind, randomized t rial. Only atenolol was found to significantly improve chest pain episodes, suggesting that it should be the preferred drug when starting pharmacologi c treatment of patients with syndrome X.