Bilateral lung volume reduction surgery was introduced into Australia in 19
95 for treatment of selected patients with emphysema. We present our experi
ence of the anaesthetic management of our first 55 cases and describe facto
rs associated with outcome. There were four postoperative deaths (7%). Mean
(SD) total operation time was 231 (72) minutes. Median intensive care unit
(ICU) stay was 26 hours. There was a significant improvement in postoperat
ive lung function (FEV1, VC, 6-minute walk test, all P < 0.001). Eight pati
ents (15%) required reintubation for respiratory failure; three of these pa
tients subsequently died. With multivariate analysis, total operation time
was the only significant predictor of length of ICU stay R-2 = 0.25, P = 0.
001), which itself was the only significant predictor of hospital stay dura
tion (R-2 = 0.36, P < 0.001).