Induction of isoflavonoid and retrochalcone branches of the flavonoid pathway in cultured Glycyrrhiza echinata cells treated with yeast extract

Authors
Nakamura, K Akashi, T Aoki, T Kawaguchi, K Ayabe, S
Citation
K. Nakamura et al., Induction of isoflavonoid and retrochalcone branches of the flavonoid pathway in cultured Glycyrrhiza echinata cells treated with yeast extract, BIOS BIOT B, 63(9), 1999, pp. 1618-1620
Citations number
17
Categorie Soggetti
Agricultural Chemistry","Biochemistry & Biophysics
Journal title
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY
ISSN journal
09168451 → ACNP
Volume
63
Issue
9
Year of publication
1999
Pages
1618 - 1620
Database
ISI
SICI code
0916-8451(199909)63:9<1618:IOIARB>2.0.ZU;2-X
Abstract
Yeast extract-treated suspension cultures of a new cell line, AK-1, of Glyc yrrhiza echinata were induced to produce an isoflavonoid phytoalexin (medic arpin) and metabolites of retrochalcone/flavone pathway (echinatin, licodio ne, and 7,4'-dihydroxyflavone). From these cells, putative full-length cDNA s encoding cytochrome P450s, (2S)-flavanone 2-hydroxylase and isoflavone 2' -hydroxylase, were cloned.