Separation of copolymers of variable compositions by capillary zone electrophoresis

Capillary zone electrophoresis (CZE) analysis of several copolymers obtaine d by radical copolymerization of acrylamide and N,N'-dimethylacrylamide usi ng acrylic acid and 1-vinyl-2-pyrrolidone as comonomers under different fee d molar ratios had been carried out. Results demonstrate that absolute valu e of the electrophoretic mobility is strongly dependent of the linear charg e density of the copolymer in agrement with the Manning's counterion conden sation theory. Analyses were performed in under 15 minutes using a phosphat e or berate buffer.