S. Regele et al., Sevum p53 autoantibodies in patients with minimal lesions of ductal carcinoma in situ of the breast, BR J CANC, 81(4), 1999, pp. 702-704
Five of 43 patients (11.6%) with ductal carcinoma in situ of the breast pre
sented with p53 autoantibodies at diagnosis. Three seropositive patients de
monstrated tumour sizes of less than or equal to 5 mm. There was no associa
tion of p53 autoantibody status with age, clinical presentation, histologic
al subtype, tumour size, grading, p53 immunohistochemistry or hormone recep
tor status. (C) 1999 Cancer Research Campaign.