A 78 year old female developed polyneuropathy, weight loss, malaise, and jo
int pain. Necrotizing vasculitis was diagnosed at hysterectomy, and later r
enal biopsy demonstrated focal segmental necrotizing glomerulonephritis. Th
e pathological findings together with the presence of pANCA was consistent
with a diagnosis of microscopic polyangiitis (MPA). This is the first clini
cal description of MPA with involvement of the uterus.