5 CASES OF FORENSIC SHORT TANDEM REPEAT DNA TYPING

Citation
C. Schmitt et M. Benecke, 5 CASES OF FORENSIC SHORT TANDEM REPEAT DNA TYPING, Electrophoresis, 18(5), 1997, pp. 690-694
Citations number
53
Categorie Soggetti
Biochemical Research Methods
Journal title
ISSN journal
01730835
Volume
18
Issue
5
Year of publication
1997
Pages
690 - 694
Database
ISI
SICI code
0173-0835(1997)18:5<690:5COFST>2.0.ZU;2-P
Abstract
In medicolegal samples DNA is often broken into fragments. In many cas es, only the amplification of short tandem repeated DMA stretches (STR s), which are located in noncoding regions, allows DNA typing of such degraded materials. To demonstrate the high diversity of biological ma terials which forensic biologists have to deal with, and to outline th e success rates and limits of the method, we describe five cases (minu te amount of tissue on barrel, tissue in decay, tumor tissue, sperm af ter multiple rape, stored urine samples) in which forensic DNA typing was successfully performed by use of the short tandem repeats HUMDHFRP 2, HUMD8S306, HUMCD4, HUMF13A1, HUMTH01, HUMVWA, and HUMFES.