Sk. Garg et al., Correlation at fingerstick blood glucose measurements with GlucoWatch biographer glucose results in young subjects with type 1 diabetes, DIABET CARE, 22(10), 1999, pp. 1708-1714
OBJECTIVE - The purpose of this study was to compare measurements of glucos
e obtained via iontophoretic extraction with the GlucoWatch automatic gluco
se biographer (Cygnus, Inc., Redwood City CA) with capillary blood glucose
values that were determined 1) in a controlled outpatient clinic setting an
d 2) in a home setting.
RESEARCH DESIGN AND METHODS - There were 76 GlucoWatch biographers used on
28 different young adults (21 women and 7 men) with type 1 diabetes (age 30
.9 +/- 6.9 years and duration of diabetes 18.4 +/- 8.1 years [mean +/- SD])
in a controlled outpatient clinic setting. Some subjects participated on m
ultiple days. Subjects wore two GlucoWatch biographers, each on the forearm
(ventral aspect). Comparisons were made to HemoCue blood glucose analyzer
(Aktiebolgat Leo, Helsingborg, Sweden) capillary blood glucose measurements
, In addition, Gluco-Watch biographers (one each day for 3 consecutive days
) were used by 12 subjects (8 women, 4 men) in a home setting. Comparisons
were made to capillary blood glucose values determined using the One Touch
Profile meter (Johnson & Johnson, Nem Brunswick, NJ).
RESULTS - GlucoWatch biographer glucose values correlated well with capilla
ry blood glucose values determined using the HemoCue analyzer in the clinic
setting (r = 0.90, 1,554 paired data points) and using the One Touch Profi
le meter in the home setting (r = 0.85, 204 paired data points). When 36 su
bjects wore two biographers simultaneously, the correlation between the two
biographers was r = 0.94. The error grid analysis demonstrated that >96% o
f biographer glucose values determined in the clinic or home setting were i
n the clinically acceptable A and B regions.
CONCLUSIONS - This study confirms the accuracy and precision of glucose val
ues as determined using the GlucoWatch biographer in clinic and home settin
gs.