Aims Young people in Russia with diabetes have an increased morbidity and a
10-fold increase in mortality compared with many European countries. This
joint international study was set up to compare of care and outcomes agains
t published guidelines in three Russian centres and one UK centre,
Methods An assessment of the diabetic care of 368 children, based on the pr
inciples of the St Vincent Declaration, was undertaken in each centre, Data
on prevalence, management, control and complications were collected in you
ng people with diabetes < 16 years of age in each of the four centres over
a 4-week period.
Results The prevalence of diabetes was greater in Southampton (1:702 vs. 1:
1378). At diagnosis Russian children had a higher incidence of ketoacidosis
(69 vs. 29%) and stayed in hospital longer (30 vs. 3 days). In management
Russian children received more injections per day (5 vs. 2). There was no s
ignificant difference in insulin dose for those under 10 years between coun
tries (Southampton 0.69 U/kg vs. Russian 0.73 U/kg, P=NS). Older Russian ch
ildren did not increase their insulin dosage, while children over 10 years
in Southampton received significantly more insulin than the Russian childre
n (Southampton 1.0 U/kg vs. Russian 0.77 U/kg, P less than or equal to 0.00
1). Twenty-nine per cent of the Russian children reported that they had ins
ufficient insulin and 14% had to buy extra. HbA(1c) was higher in the Russi
an children (9.8% vs. 8.3%), increasing significantly with age. The Russian
children showed a height deficit which correlated with HbA(1c) and diabete
s duration. The Southampton children were heavier and with a higher body-ma
ss index and their HbA(1c) did not rise similarly as in Russia. Severe hypo
glycaemia was more common in the Southampton children (32 vs. 12%). Retinop
athy was reported in 12% of the Russian children (Southampton 0%) and systo
lic blood pressure > 95th centile in 21% (Southampton 8%).
Conclusions This study demonstrates a significant difference in diabetic co
ntrol and complications between the two countries which could be partially
explained by a decreased availability and prescribing of insulin and blood
glucose monitoring in Russia. Southampton has an education and management p
olicy based on ambulatory care resulting in reduced hospital stay.