Integration of receptor-mediated signals in T cells by transmembrane adaptor proteins

Authors
Schraven, B Marie-Cardine, A Hubener, C Bruyns, E Ding, I
Citation
B. Schraven et al., Integration of receptor-mediated signals in T cells by transmembrane adaptor proteins, IMMUNOL TOD, 20(10), 1999, pp. 431-434
Citations number
23
Categorie Soggetti
Immunology
Journal title
IMMUNOLOGY TODAY
ISSN journal
01675699 → ACNP
Volume
20
Issue
10
Year of publication
1999
Pages
431 - 434
Database
ISI
SICI code
0167-5699(199910)20:10<431:IORSIT>2.0.ZU;2-B
Abstract
Our knowledge of the molecular events leading to T-cell activation has not yet fully explained how intracellular effector molecules are recruited to t he plasma membrane after engagement of the TCR by antigen-MHC. The identifi cation of transmembrane adaptor proteins might help to elucidate the mechan isms involved.