Health care workers (HCW), especially women (for example, pediatric nurses
and day nursery workers), have been shown to be at risk for viral hepatitis
A infections. In order to obtain a more precise estimate of the risk in Be
lgian HCW, a seroprevalence study was undertaken. The data from this study
have been compared with the age-specific seroprevalence of anti-HAV in the
general population (CP) as recently estimated. During 1996-1997, a sample o
f 5,068 employees in 22 general hospitals, geographically distributed over
the Flemish and Brussels regions of Belgium, was tested for the presence of
anti-HAV. Comparison of the anti-HAV prevalences in HCW and CP shows a sig
nificantly lower prevalence in HCW for the age groups 25-34, 35-44 and 45-5
4 years. Within these age-groups, employees performing catering tasks have
the highest prevalence. This difference could be explained by socioeconomic
parameters: overrepresentation of higher social classes in better educated
HCW. The number of unprotected individuals in young and older age groups (
25-54 years) is greater than in the general population. In view of the chan
ging HAV epidemiology in western Europe, the number of unprotected persons
will rise in the coming years. Considering the more severe course of the di
sease as age increases, vaccination may become important in the occupationa
l health strategy for HCW.