Type III secretion-dependent hemolytic activity of enteropathogenic Escherichia coli

Authors
Warawa, J Finlay, BB Kenny, B
Citation
J. Warawa et al., Type III secretion-dependent hemolytic activity of enteropathogenic Escherichia coli, INFEC IMMUN, 67(10), 1999, pp. 5538-5540
Citations number
26
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
67
Issue
10
Year of publication
1999
Pages
5538 - 5540
Database
ISI
SICI code
0019-9567(199910)67:10<5538:TISHAO>2.0.ZU;2-D
Abstract
Enteropathogenic Escherichia call (EPEC) was found to exhibit a type III se cretion-dependent, contact-mediated, hemolytic activity requiring the EspA, EspB, and EspD secreted proteins. EspB and EspD display homology to pore-f orming molecules. Our data suggest a mechanism to explain the requirement f or an three Esp proteins in the transfer of EPEC proteins, such as Tir, int o target cells.