Growth rate of mycobacteria in mice as an unreliable indicator of mycobacterial virulence

Authors
North, RJ Ryan, L LaCource, R Mogues, T Goodrich, ME
Citation
Rj. North et al., Growth rate of mycobacteria in mice as an unreliable indicator of mycobacterial virulence, INFEC IMMUN, 67(10), 1999, pp. 5483-5485
Citations number
17
Categorie Soggetti
Immunology
Journal title
INFECTION AND IMMUNITY
ISSN journal
00199567 → ACNP
Volume
67
Issue
10
Year of publication
1999
Pages
5483 - 5485
Database
ISI
SICI code
0019-9567(199910)67:10<5483:GROMIM>2.0.ZU;2-E
Abstract
The CDC1551 strain of Mycobacterium tuberculosis was compared with the H37R v strain of M. tuberculosis and the Ravenel strain of Mycobacterium bovis f or virulence in mice. Although all three strains gave rise to the same leve l of stationary infection in major organs, mice infected with the Ravenel s train died much earlier from lung disease.