Low dose synthetic human atrial natriuretic peptide infusion in a patient with mitral stenosis and severe pulmonary hypertension

Authors
Maeda, K Tsutamoto, T Wada, A Hisanaga, T Nishimura, T Yamada, H Sasaki, Y Kinoshita, M
Citation
K. Maeda et al., Low dose synthetic human atrial natriuretic peptide infusion in a patient with mitral stenosis and severe pulmonary hypertension, JPN CIRC J, 63(10), 1999, pp. 816-818
Citations number
13
Categorie Soggetti
Cardiovascular & Respiratory Systems","Cardiovascular & Hematology Research
Journal title
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION
ISSN journal
00471828 → ACNP
Volume
63
Issue
10
Year of publication
1999
Pages
816 - 818
Database
ISI
SICI code
0047-1828(199910)63:10<816:LDSHAN>2.0.ZU;2-O
Abstract
The present report concerns a case of very low plasma levels of atrial natr iuretic peptide (ANP) accompanying severe pulmonary hypertension due to mit ral stenosis. There was remarkable fibrosis in the atrium and ANP secretion may have been insufficient. Low-dose infusion (0.025 mu g kg(-1) min(-1)) of synthetic human alpha-ANP infusion was very effective in improving the p ulmonary hypertension.