A 57-year-old male with primary cardiac angiosarcoma was initially admitted
for cardiac tamponade. Pericardiocentesis was performed twice preoperative
ly, but the bloody pericardial fluid was cytologically negative for maligna
nt cells. The tumor in the right atrium was resected during cardiopulmonary
bypass. The resected tumor was 5.5x4.5x3.0cm in size and the diagnosis of
cardiac angiosarcoma was made histologically. There were no tumor cells in
the surgical margin. Unfortunately the patient died 3.5 months after surger
y due to multiple recurrence in the pericardium. A suitable therapy for car
diac angiosarcoma is still controversial, but early antemortem diagnosis an
d more aggressive combined treatment should be considered.