Ophthalmological signs in inherited epidermolysis bullosa: a series of 40 cases

Introduction: We assessed the frequency of ophthalmologic signs in inherite d epidermolysis bullosa and evaluated follow-up. Patients and methods : Forty patients were studied retrospectively. Of the 40 patients, 38 had dystrophic and 2 had junctional epidermolysis bullosa. A complete ocular examination was performed in all cases and repeated if: n ecessary (8 times). Results: Ocular complications were found in 75% of the patients. Corneal an omalies associated or not with refractive anomalies were present. The best corrected visual acuity was less than 3/10 in 20% of the cases. Only 15% ha d lid modifications. Discussion : In our series, 75% of the cases had ocular anomalies, similar to other series in the literature. Corneal problems dominated. Conclusion : Ocular lesions in inherited epidermolysis bullosa are often fo und and require initial ocular examination. Corneal lesions also need to be followed with optical correction to optimize functional prognosis.