Background: psychomotor retardation in depression has mostly been assessed
with tasks requiring both cognitive and motor processes. This study tested
whether retardation could be measured if the cognitive demands of the task
were minimal. Methods: 30 inpatients with a major depressive episode were c
ompared one week after the start of antidepressant treatment, to 30 healthy
control persons, matched for age, sex and educational level. Tests consist
ed of ten simple drawing tasks. The kinematics of drawing movements were re
corded using a specially designed pen, a graphics tablet and a personal com
puter. Results: patients showed marked motor slowing on all the tasks: long
er movement durations, longer pauses and lower velocities. Conclusions: psy
chomotor retardation in depressed patients treated with antidepressants occ
urs during drawing tasks, in which the cognitive demands are minimal and le
ss than those required in the figure copying tasks used in our previous stu
dies. Limitations: the use of co-medication can have influenced the results
, although no correlations were found between the use of medication and the
kinematic variables. Clinical relevance: detailed registration and analysi
s of drawing movements enable a more precise diagnosis of psychomotor distu
rbances in depressed patients. (C) 1999 Elsevier Science B.V. All rights re
served.