The magnitude of the effect of smaller family sizes on the increase in theprevalence of asthma and hay fever in the United Kingdom and New Zealand

Citation
K. Wickens et al., The magnitude of the effect of smaller family sizes on the increase in theprevalence of asthma and hay fever in the United Kingdom and New Zealand, J ALLERG CL, 104(3), 1999, pp. 554-558
Citations number
40
Categorie Soggetti
Clinical Immunolgy & Infectious Disease",Immunology
Journal title
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
ISSN journal
00916749 → ACNP
Volume
104
Issue
3
Year of publication
1999
Part
1
Pages
554 - 558
Database
ISI
SICI code
0091-6749(199909)104:3<554:TMOTEO>2.0.ZU;2-7
Abstract
Background: Declining family size is one factor that has been proposed to c ontribute to increasing asthma and hay fever prevalence, but its relative i mportance has not been quantified. Objective: Our purpose was to determine the change in asthma and hay fever prevalence that would be expected from the reduction in family size that ha s occurred in England/Wales and New Zealand over recent decades, Methods: The relative change in family size between 1961 and 1991 in Englan d/Wales and New Zealand was determined from census data for these years. Su mmary weighted odds ratios were calculated for the associations among birth order, family size, and asthma and hay fever prevalence. The expected incr ease in the prevalence of asthma and hay fever between 1961 and 1991 result ing from changes in family size was then calculated. Results: The expected relative increase in the prevalence of asthma between 1961 and 1991 as a result of the smaller family size was 1% and 5% for Eng land/Wales and New Zealand, respectively; smaller family size mould be expe cted to increase the prevalence of hay fever prevalence in England/Wales by 4%. Conclusions: Changes in family size over the last 30 years do not appear to explain much of the reported increase in asthma or hay fever prevalence. T he contribution that other risk factors have made to these increases could be assessed with use of a similar approach.