Decatromicins A and B, new antibiotics produced by Actinomadura sp MK73-NF4 - I. Taxonomy, isolation, physico-chemical properties and biological activities
I. Momose et al., Decatromicins A and B, new antibiotics produced by Actinomadura sp MK73-NF4 - I. Taxonomy, isolation, physico-chemical properties and biological activities, J ANTIBIOT, 52(9), 1999, pp. 781-786
New antibiotics designated decatromicins A and B were isolated from the cul
ture broth of Actinomadura sp. MK73-NF4. They were purified by butyl acetat
e extraction, silica gel column chromatography, silica gel TLC and Sephadex
LH-20 column chromatography. Decatromicins A and B inhibited growth of Gra
m-positive bacteria including methicillin-resistant Staphylococcus aureus (
MRSA).