recD sbcB sbcD mutants are deficient in recombinational repair of UV lesions by RecBC

Authors
Seigneur, M Ehrlich, SD Michel, B
Citation
M. Seigneur et al., recD sbcB sbcD mutants are deficient in recombinational repair of UV lesions by RecBC, J BACT, 181(19), 1999, pp. 6220-6221
Citations number
13
Categorie Soggetti
Microbiology
Journal title
JOURNAL OF BACTERIOLOGY
ISSN journal
00219193 → ACNP
Volume
181
Issue
19
Year of publication
1999
Pages
6220 - 6221
Database
ISI
SICI code
0021-9193(199910)181:19<6220:RSSMAD>2.0.ZU;2-D
Abstract
In reD sbcB sbcD mutants, repair of UV-irradiated DNA is strongly Reef depe ndent, indicating that RecBC is inactive. This finding suggests that exonuc lease V, exonucleas I (SbcB), and the SbcCD nuclease play a redundant role in vivo, which is essential for the recombination activity of the RecBC com plex during UV repair.