New bromopyrrole alkaloids from the indopacific sponge Agelas nakamurai

Authors
Eder, C Proksch, P Wray, V van Soest, RWM Ferdinandus, E Pattisina, LA",Sudarsono
Citation
C. Eder et al., New bromopyrrole alkaloids from the indopacific sponge Agelas nakamurai, J NAT PROD, 62(9), 1999, pp. 1295-1297
Citations number
10
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
62
Issue
9
Year of publication
1999
Pages
1295 - 1297
Database
ISI
SICI code
0163-3864(199909)62:9<1295:NBAFTI>2.0.ZU;2-2
Abstract
Two new dimeric bromopyrrole alkaloids, nakamuric acid (1) and its correspo nding methyl ester (2), have been isolated from the Indopacific sponge Agel as nakamurai along with the known metabolites sceptrin (3), debromosceptrin (4), and ageliferin (5). Their structures were identified by analysis of s pectral data. All compounds inhibited the growth of several Gram-positive a nd Gram-negative bacteria in the agar plate diffusion assay.