Antibacterial diterpenoid acids from Azorella compacta

Authors
Wachter, GA Matooq, G Hoffmann, JJ Maiese, WM Singh, MP Montenegro, G Timmermann, BN
Citation
Ga. Wachter et al., Antibacterial diterpenoid acids from Azorella compacta, J NAT PROD, 62(9), 1999, pp. 1319-1321
Citations number
5
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
62
Issue
9
Year of publication
1999
Pages
1319 - 1321
Database
ISI
SICI code
0163-3864(199909)62:9<1319:ADAFAC>2.0.ZU;2-S
Abstract
The two novel diterpenoid acids mulin-12,14-dien-11-on-20-oic acid (1) and mulin-12-ene-11,14-dion-20-oic acid (2) have been isolated from Azorella co mpacta. Their structures have been elucidated by 1D and 2D NMR methods. In contrast to the closely related known mulinolic acid (3) and its dehydratio n product (4) these new natural products have been shown to exhibit antimic robial activity.