New antimycobacterial saponin from Colubrina retusa

Citation
Hn. Elsohly et al., New antimycobacterial saponin from Colubrina retusa, J NAT PROD, 62(9), 1999, pp. 1341-1342
Citations number
3
Categorie Soggetti
Agricultural Chemistry","Pharmacology & Toxicology
Journal title
JOURNAL OF NATURAL PRODUCTS
ISSN journal
01633864 → ACNP
Volume
62
Issue
9
Year of publication
1999
Pages
1341 - 1342
Database
ISI
SICI code
0163-3864(199909)62:9<1341:NASFCR>2.0.ZU;2-W
Abstract
A new jujubogenin saponin was isolated from the stems of Colubrina retusa a nd identified as jujubogenin 3-O-alpha-L-arabinofuranosyl (1-->2)-[3-O-(tra ns)-p-coumaroyl-beta-D-glucopyranosyl (1-->3)]-alpha-L-arabinopyranoside (4 ) on the basis of chemical and spectroscopic data. The antimycobacterial ac tivity expressed as minimum inhibitory concentration (MIC) for compound 4 w as 10 mu g/mL.