To assess of the value of conservative and operative treatment of osteochon
dritis dissecans of the knee, a multicenter study was performed. In 12 Euro
pean countries, 798 cases of osteochondritis of the knee have been collecte
d from 44 hospitals. Results were based on 452 patients with 509 affected k
nees with minimum follow-up was 1 year (mean follow-up. 3 years and 11 mont
hs) and sufficient data for evaluation: 61% were male patients; 39% female
patients; 318 affected knees were found in juvenile patients; 191 affected
knees were in adult or premature patients. The localization was the medial
femoral condyle on the lateral side in 51% (typical site) of patients. Vari
ous other sites were involved. Of the 509 affected knees, 154 were treated
conservatively, 355 were treated surgically (many with multiple operations)
. For evaluation, the initial situation (at the time of the diagnosis) was
favorable in 198 patients (no effusion, diameter of the lesion <20 mm and n
o gross dissection on imaging) and unfavorable (one of the parameters did n
ot meet these prerequisites) in 311 patients. The results were better in yo
ung patients than in adult patients. However, in the adolescent group, 22%
of patients had abnormal knee at follow-up. The classical localization has
a better prognosis than an unusual one. Patients with a favorable situation
at diagnosis have significantly better results after conservative treatmen
t than those who have undergone operation. When there are signs of dissecti
on, the results are better after operative than after conservative treatmen
t.