ALDOL-CYCLIZATION REACTION SEQUENCE FOR THE SYNTHESIS OF TETRAHYDROFURANS

Authors
CALTER MA SUGATHAPALA PM ZHU C
Citation
Ma. Calter et al., ALDOL-CYCLIZATION REACTION SEQUENCE FOR THE SYNTHESIS OF TETRAHYDROFURANS, Tetrahedron letters, 38(22), 1997, pp. 3837-3840
Citations number
12
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
22
Year of publication
1997
Pages
3837 - 3840
Database
ISI
SICI code
0040-4039(1997)38:22<3837:ARSFTS>2.0.ZU;2-6
Abstract
The aldol reactions of alpha-diazo-beta-ketoesters with a variety of a ldehydes produced adducts which underwent Rh(II)-catalyzed O-H inserti on reaction to yield highly substituted tetrahydrofurans. Alkylation a nd decarboxylation of these tetrahydrofurans formed a wide variety of tetrahydrofuran structures. (C) 1997 Elsevier Science Ltd.