ASYMMETRIC-SYNTHESIS OF UNUSUAL AMINO-ACID - SYNTHESIS OF 4 ISOMERS OF BETA-METHYL-3-(2'-NAPHTHYL)ALANINE

Authors
YUAN W HRUBY VJ
Citation
W. Yuan et Vj. Hruby, ASYMMETRIC-SYNTHESIS OF UNUSUAL AMINO-ACID - SYNTHESIS OF 4 ISOMERS OF BETA-METHYL-3-(2'-NAPHTHYL)ALANINE, Tetrahedron letters, 38(22), 1997, pp. 3853-3856
Citations number
21
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron letters → ACNP
ISSN journal
00404039
Volume
38
Issue
22
Year of publication
1997
Pages
3853 - 3856
Database
ISI
SICI code
0040-4039(1997)38:22<3853:AOUA-S>2.0.ZU;2-J
Abstract
The synthesis of all four individual isomers of 3-methyl-3-(2'-naphthy l)analine was accomplished using asymmetric conjugate 1,4-addition fol lowed by direct or indirect azidation using an Evans-type chiral auxil iary (4-phenyl-2-oxazolidinone). (C) 1997 Elsevier Science Ltd.