Distinguishing diastereomeric organic compounds based on the concerted useof (3)J(C,H) and (3)J(N,H) values

Authors
Groger, S Josey, JA Poppe, L
Citation
S. Groger et al., Distinguishing diastereomeric organic compounds based on the concerted useof (3)J(C,H) and (3)J(N,H) values, MAGN RES CH, 37(10), 1999, pp. 748-750
Citations number
14
Categorie Soggetti
Spectroscopy /Instrumentation/Analytical Sciences
Journal title
MAGNETIC RESONANCE IN CHEMISTRY
ISSN journal
07491581 → ACNP
Volume
37
Issue
10
Year of publication
1999
Pages
748 - 750
Database
ISI
SICI code
0749-1581(199910)37:10<748:DDOCBO>2.0.ZU;2-6
Abstract
The relative stereochemistry of the two acyclic carbons separated by a sing le bond was determined from three-bond homo- and heteronuclear coupling con stants. The analysis of data was based on a purely qualitative interpretati on of the Karplus relationships. The methodology presented could resolve ac yclic diastereoisomers if adequate sets of three-bond coupling constants ca n be measured. Copyright (C) 1999 John Wiley & Sons, Ltd.