We have cloned c-Irx2, a chick homologue of the Xiro2 and mIrx2 genes and a
new member of the Iroquois family of homeodomain-containing transcription
factors. Strikingly, c-Irx2 expression reveals an early subdivision of the
neural plate at late primitive streak stages which later transiently resolv
es to a single stripe within the developing hindbrain corresponding to rhom
bomere 1. (C) 1999 Elsevier Science Ireland Ltd. All rights reserved.