"Pseudo-conduction block" in vasculitic neuropathy

Citation
L. Mccluskey et al., "Pseudo-conduction block" in vasculitic neuropathy, MUSCLE NERV, 22(10), 1999, pp. 1361-1366
Citations number
28
Categorie Soggetti
da verificare
Journal title
MUSCLE & NERVE
ISSN journal
0148639X → ACNP
Volume
22
Issue
10
Year of publication
1999
Pages
1361 - 1366
Database
ISI
SICI code
0148-639X(199910)22:10<1361:"BIVN>2.0.ZU;2-6
Abstract
The predominant electrophysiologic feature of vasculitic mononeuropathy mul tiplex is axonal loss. Electrophysiologic findings interpreted as conductio n block have, however, also been reported to occur in neuropathy secondary to necrotizing vasculitis. We report 3 patients with mononeuropathy multipl ex and biopsy proven vasculitis in whom eight nerves met criteria for condu ction block. In each circumstance, serial study demonstrated conversion of the electrophysiologic findings to those most consistent with severe axonal loss. "Conduction block" in vasculitic mononeuropathy multiplex is seconda ry to focal axonal conduction failure presumably related to infarctive axon al injury. The term conduction block should be used with caution in this di sorder and only if serial studies demonstrate findings consistent with this electrophysiologic diagnosis. (C) 1999 John Wiley & Sons, Inc.