Twenty-two laundry personnel at St. Luke's Hospital, Malta, were tested for
seropositivity to hepatitis A together with 37 nursing aides working in pa
ediatric and infectious disease wards, matched for age, who were used as co
ntrols. IgG antibodies were found in 54.5% of laundry workers and 13.5% of
nursing aides [odds ratio (OR) = 7.68; 95% confidence interval (CI) = 1.87-
33.83]. Furthermore, laundry personnel consistently handling dirty linen pr
ior to washing showed an OR of 16.50 (CI = 1.19-825.57) as compared with co
lleagues handling only clean items. These results would suggest that the in
creased exposure of hospital laundry workers to potentially infected linen
can constitute a risk of occupational hepatitis A for this group of employe
es.