Objective: To study the effectiveness of neodymium:YAG (Nd:YAG) laser trans
conjunctival revision of late-failing filtering blebs,
Design: Retrospective, noncomparative case series,
Participants: Thirty consecutive patients from a glaucoma referral practice
at the Ohio State University Department of Ophthalmology,
Intervention: Transconjunctival Nd,YAG laser revision of blebs diagnosed as
failing secondary to episcleral fibrosis,
Main Outcome Measure: Reduction in intraocular pressure (IOP) and survival
of bleb,
Results: Reduction in IOP was attained in 24 (80%) of 30 patients with a me
an prelaser IOP of 21.21 mmHg and a mean 1-week postlaser IOP of 13.97 mmHg
(P < 0.0001). These results were maintained at the 1-, 3-, and 12-month fo
llow-up visits with mean IOPs of 16.31 mmHg (P = 0.0008), 14.81 mmHg (P < 0
.0001), and 15.25 mmHg (P = 0.0003), respectively. Two-year data were avail
able on a small number of patients (4) with a mean of 15.25 mmHg (P = 0.008
5), Mean time interval between trabeculectomy and laser revision was 31 mon
ths,
Conclusion: Late-failing filtering blebs are often amenable to Nd:YAG trans
conjunctival revision.