Prebiotic formation of ADP and ATP from AMP, calcium phosphates and cyanate in aqueous solution

Adenosine-5'-triphosphate was synthesized by the phosphorylation of adenosi ne-5'-diphosphate in aqueous solution containing cyanate as a condensing re agent and insoluble calcium phosphate produced from phosphate and calcium c hloride. In a similar manner, adenosine-5'-diphosphate was synthesized from adenosine-5'-monophosphate. When the experiment was carried out in the con ditions of 4 degrees C and pH 5.75, the formation of adenosine-5'-diphospha te and adenosine-5'-triphosphate from adenosine-5'-monophosphate was observ ed in the yields of 19 and 7%, respectively. The other nucleoside-5'-tripho sphates were also produced from their respective diphosphates.