Condensation reaction of beta-triphenylgermanyl propanoic acid with diphenyl alpha-aminophosphonates and bioactivities of products

Authors
Wang, QM Zeng, Q
Citation
Qm. Wang et Q. Zeng, Condensation reaction of beta-triphenylgermanyl propanoic acid with diphenyl alpha-aminophosphonates and bioactivities of products, PHOSPHOR SU, 148, 1999, pp. 41-49
Citations number
5
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
ISSN journal
10426507 → ACNP
Volume
148
Year of publication
1999
Pages
41 - 49
Database
ISI
SICI code
1042-6507(1999)148:<41:CROBPA>2.0.ZU;2-F
Abstract
The condensation reaction of beta-triphenylgermanyl propanoic acid with dip henyl alpha-aminophosphonates was studied. A variety of novel diphenyl N-tr iphenylgermanylpropiono-alpha-aminophosphonates were synthesized successful ly in good yields by using DCC catalyzed by pyridine. The structures of all of the products were confirmed by (HNMR)-H-1, (PNMR)-P-31, IR, MS and elem ental analysis. The results of bioassay showed that the new products have g ood anticancer activities and very strong anti-inflammatory activities.