Synthesis of novel derivatives of 2-cyano-3-methylthio-3 '-benzylamino acrylates(acrylamides) and their biological activity

Authors
Liu, HY Sha, YL Dai, GX Tan, HF Yang, HZ Lai, LH
Citation
Hy. Liu et al., Synthesis of novel derivatives of 2-cyano-3-methylthio-3 '-benzylamino acrylates(acrylamides) and their biological activity, PHOSPHOR SU, 148, 1999, pp. 235-241
Citations number
7
Categorie Soggetti
Inorganic & Nuclear Chemistry
Journal title
PHOSPHORUS SULFUR AND SILICON AND THE RELATED ELEMENTS
ISSN journal
10426507 → ACNP
Volume
148
Year of publication
1999
Pages
235 - 241
Database
ISI
SICI code
1042-6507(1999)148:<235:SONDO2>2.0.ZU;2-F
Abstract
A series of new substituted derivatives of 2-cyano-3-methvlthio-3'-aminoacr ylates(acrylamides) have been designed and synthesized. Their structures we re confirmed by H-1 NMR and elemental analysis. The bioassay test indicates that most of these new compounds show good Hill reaction inhibitory activi ty.