In vitro antitrypanosomal activity of Moringa stenopetala leaves and roots

Authors
Mekonnen, Y Yardleg, V Rock, P Croft, S
Citation
Y. Mekonnen et al., In vitro antitrypanosomal activity of Moringa stenopetala leaves and roots, PHYTOTHER R, 13(6), 1999, pp. 538-539
Citations number
11
Categorie Soggetti
Pharmacology & Toxicology
Journal title
PHYTOTHERAPY RESEARCH
ISSN journal
0951418X → ACNP
Volume
13
Issue
6
Year of publication
1999
Pages
538 - 539
Database
ISI
SICI code
0951-418X(199909)13:6<538:IVAAOM>2.0.ZU;2-1
Abstract
The leaves and the root extracts of Moringa stenopetala were tested in vitr o against trypomastigotes of Trypanosoma brucei, Trypanosoma cruzi and L. d onovani amastigotes, The fresh root wood ethanol extract and the dried leav es acetone extract were found to be active against T. brucei with an ED50 v alue of 9.2 mu g/mL and 10.0 mu g/mL respectively, All the other extracts w ere inactive against all the tested parasite forms. Copyright (C) 1999 John Wiley & Sons, Ltd.