VICINAL TETRAHYDROFURAN POLYSUBSTITUTION OF SIMULATED FATTY-ACIDS

Authors
STEPANIAN M TREGO WE BOLIN DG PAQUETTE LA SARETH S RIDDELL FG
Citation
M. Stepanian et al., VICINAL TETRAHYDROFURAN POLYSUBSTITUTION OF SIMULATED FATTY-ACIDS, Tetrahedron, 53(22), 1997, pp. 7403-7416
Citations number
24
Categorie Soggetti
Chemistry Inorganic & Nuclear
Journal title
Tetrahedron → ACNP
ISSN journal
00404020
Volume
53
Issue
22
Year of publication
1997
Pages
7403 - 7416
Database
ISI
SICI code
0040-4020(1997)53:22<7403:VTPOSF>2.0.ZU;2-B
Abstract
Two groups of tetrahydrofuranyl-substituted long-chain carboxylic acid s have been prepared under total stereochemical control. The diastereo meric ionophores were subsequently evaluated for their capability of b inding alkali metal ions computationally by Amber force field calculat ions, experimentally by means of the picrate extraction method, and by mediating the transport of Lif and Naf through phospholipid bilayers. (C) 1997 Elsevier Science Ltd.