First total synthesis of cryptomisrine

Authors
Arzel, E Rocca, P Marsais, F Godard, A Queguiner, G
Citation
E. Arzel et al., First total synthesis of cryptomisrine, TETRAHEDRON, 55(41), 1999, pp. 12149-12156
Citations number
21
Categorie Soggetti
Chemistry & Analysis","Organic Chemistry/Polymer Science
Journal title
TETRAHEDRON
ISSN journal
00404020 → ACNP
Volume
55
Issue
41
Year of publication
1999
Pages
12149 - 12156
Database
ISI
SICI code
0040-4020(19991008)55:41<12149:FTSOC>2.0.ZU;2-#
Abstract
The first total synthesis of cryptomisrine, a novel indolo[3,2-b]quinoline dimeric alkaloid from Cryptolepis sanguinolenta, is reported. The approach is based on a convergent methodology which involves a new halogen-dance rea ction in quinoline series connected to a cross-coupling reaction. (C) 1999 Elsevier Science Ltd. All rights reserved.