Hieronymus Bosch and other early Renaissance artists depicted 'stone operat
ions' In which stones were supposedly surgically removed from the head as a
treatment for mental illness. These works have usually been interpreted ei
ther as portraying a contemporary practice of medical charlatans or as an a
llegory of human folly, rather than a real event. As trepanation for head i
njury and mental disease was actually carried out in Europe at this time, a
nother interpretation of these works is that they are derived from a common
medical practice of the day.